Table 9.

MutY excision of nucleobase analogs opposite OG within 30 bp DNA substrates.

Nucleobase analog	kg (min−1)a	Fold reduced relative to OG:A substrate
A	12 ± 2c	---
Q (4)	1.2 ± 0.2c	10x
Z1 (3)	0.31 ± 0.06	40x
Z3 (2)	0.10 ± 0.05b	100x
B (6)	< 0.002c	6000x
M (5)	NCd,e	>24,000x
Z (1)	NCe	>24,000x

^aRates were measured at 37° C. Errors represent standard deviation from the average.

^bValue previously reported (reference²⁶).

^cValue previously reported (reference²⁵).

^dNot cleaved above detection limit (<0.0005 min⁻¹).

^eValue previously reported (reference²⁷).

fValue previously reported (reference²⁸).