Table 3. Target blood phenylalanine concentrations (µmol/L) as recommended for treatment of PKU in different countries.
Age group | United States | UK | Japan | Turkey | China |
< 2 years | 120 – 360 | 120 – 360 | 120 – 240 | 60 – 240 | 120 – |
2–6 years | 120 – 360 | ||||
7–9 years | 120 – 480 | 180 – 360 | |||
10–12 years | 180 – 480 | ||||
13–15 years | 120 – 600 | 120 – 700 | 180 – 600 | ||
> 16 years | 120 – 900 | 180 – 900 | |||
Incidence | 1/15,000 | 1/10,000 | 1/70,000 | 1/4,000 | 1/11,144 |