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. 2012 May;1(2):66–80. doi: 10.5582/irdr.2012.v1.2.66

Table 1. Recent studies reporting transplantation for PBC.

Author Year Country PBC cases (n) Protocol biopsy Follow-up period (yr) mean (range) Patient survival (5-/10-year) (%) Reccurrence rate n (%) Time to recurrence (yr) Graft loss due to recurrence (n)
Sebagh et al. (167) 1998 France  69 Yes 1–10 NA   6 (9) 6.3 0
Renz et al. (168) 2002 US  58 Yes 5.3 ± 2.4 NA   8 (14) NA 2
Sanchez et al. (169) 2003 US 156 Tes 6 (1–15) NA  17 (13) 4.1 (1.1–7.1) 1
Levitsky et al. (170) 2003 US  46 No NA NA   7 (15) 6.5 (2.3–10) 0
Khettry et al. (171) 2003 US  43 No 7 (1–17) NA   8 (19) 3.5 (0.1–14) 0
Neuberger et al. (14, 172) 2004 UK 485 Yes 6.6 78/67 114 (23) 10 (cyclosporine)/5.2 (tacrolimus) 3
Guy et al. (173) 2005 US  48 No 4.2 (1–12) NA   17 (35) 3.3 ± 2.8 1
Charatcharoenwitthaya et al. (174) 2007 US 154 Yes 11 (1–21) 90/66  52 (34) 3.5 (0.3–18) 2
Morioka et al. (175) 2007 Japan  50 No 2.4 (0–10) NA   9 (18) 1.6 (0.2–5.7) 0
Campse et al. (176) 2009 US  70 No 7.8 (0.3–17) 72/54  18 (26) 4.8 (0.4–13) 0
Jacob et al. (177, 178) 2010 Germany 121 Yes 10 (0.4–19) 87/84  18 (15) 5 (3–10) 2
Montano-Loza et al. (179) 2010 Canada 108 No 7.3 (0.2–19) 86/76  28 (26) 5.8 (0.5–16) 10.8 (cyclosporine)/6 (tacrolimus) NA
Manousou et al. (180) 2010 UK 103 Yes 9 (1–20) NA  36 (35) 3.7 (1–17) 6
Kaneko et al. (181) 2011 Japan  81 No 6.2 (0.1–13) NA   1 (1) 5.1 0

Abbreviations: NA, not available; PBC, primary biliary cirrhosis