Figure 3.

DCS improved locomotion in severely DA-depleted mice and in chronically lesioned rats (Fuentes et al., 2009). (A), DCS established better efficacy in the group undergoing DCS in combination with successive l-dopa injections (black) than the group only receiving l-dopa (gray); (B), DCS (yellow shaded area) caused significant improvements of locomotion in 6-OHDA-lesioned rats (shaded area around trace is SEM); (C), (Left) DCS specifically improved locomotion in 6-OHDA-lesioned rats, (Right) Faster movement components of locomotion were also ameliorated by DCS in the 6-OHDA-lesioned rats.