Table 1.
Domain | Characteristics | Total (n=241) |
PBO (n=69) |
FLX (n=86) |
C-CT (n=86) |
---|---|---|---|---|---|
Demographic | Sex, No (%) female | 162 (67.2) | 42 (60.9) | 57 (66.3) | 63 (73.3) |
Race, No (%) white | 205 (85.1) | 62 (89.9) | 72 (83.7) | 71 (82.6) | |
Age, mean (SD) | 42.7 (11.8) | 43.6 (12.3) | 41.6(11.8) | 43.1 (11.5) | |
Marital status, No (%) | |||||
Single | 138 (57.3) | 36 (52.2) | 56 (65.1) | 46 (53.5) | |
Partnered | 103 (42.7) | 33 (47.8) | 30 (34.9) | 40 (46.5) | |
Education, mean (SD) | 15.7 (2.9) | 15.3 (3.1) | 16.0(3.0) | 15.7 (2.7) | |
Employment, No (%) | |||||
Full time | 120 (49.8) | 35 (50.7) | 44 (51.2) | 41 (47.7) | |
Part time | 28 (11.6) | 9 (13.0) | 12 (14.0) | 7 (8.1) | |
Homemaker/Caregiver | 18 (7.5) | 5 (7.3) | 4 (4.7) | 9 (10.5) | |
Student | 14 (5.8) | 2 (2.9) | 6 (7.0) | 6 (7.0) | |
Retired | 9 (3.7) | 2 (2.9) | 5 (5.8) | 2 (2.3) | |
Other | 13 (5.4) | 4 (5.8) | 3 (3.5) | 6 (7.0) | |
Unemployed | 39 (16.2) | 12 (17.4) | 12 (14.0) | 15 (17.4) | |
Severity and Clinical | HRSD17 Depression Severity Scores, mean (SD) | ||||
At final pre-treatment follow-up | 20.0 (3.9) | 20.4 (3.9) | 19.9(3.9) | 19.9(4.0) | |
At randomization | 7.5 (3.4) | 7.4 (3.0) | 7.5(3.6) | 7.5(3.4) | |
Age at onset, in years, Median | 18.0 | 19.0 | 17.0 | 19.5 | |
Length of current episode in months, Median, ¥, †, § | 9.0 | 9.0 | 6.0 | 12.5 | |
Length of illness in years, Median | 20.0 | 19.0 | 20.5 | 21.0 | |
No. of episodes, median | 4.0 | 3.0 | 4.0 | 4.0 | |
Comorbid DSM-IV diagnoses, No (%) | |||||
Current | 96 (39.8) | 26 (37.7) | 37 (43.0) | 33 (38.4) | |
Lifetime | 181 (75.1) | 51 (73.9) | 67 (77.9) | 63 (73.3) | |
Depressive subtype – N (%) | 11 (4.6) | 2 (2.9) | 5 (5.8) | 4 (4.7) | |
RDC endogenous, definite | 84 (35.2) | 26 (38.2) | 34 (40.0) | 24 (27.9) | |
DSM-IV melancholia | 85 (35.6) | 22 (32.8) | 37 (43.0) | 26 (30.2) |
: p ≤ .05 for comparing the patients in the three groups (PBO, FLX, and C-CT).
: p ≤ .05 for comparing the patients in the PBO and FLX groups.
: p ≤ .05 for comparing the patients in the PBO and C-CT groups.
: p ≤ .05 for comparing the patients in the FLX and C-CT groups.