Comparison 12. Failure to complete (inefficacy).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Citalopram versus TCAs	9	1267	Odds Ratio (M‐H, Random, 95% CI)	1.47 [0.84, 2.57]
1.1 versus Amitriptyline	4	535	Odds Ratio (M‐H, Random, 95% CI)	0.83 [0.33, 2.09]
1.2 versus Clomipramine	1	114	Odds Ratio (M‐H, Random, 95% CI)	2.48 [0.72, 8.59]
1.3 versus Imipramine	2	517	Odds Ratio (M‐H, Random, 95% CI)	1.64 [0.24, 11.24]
1.4 versus Nortriptyline	2	101	Odds Ratio (M‐H, Random, 95% CI)	2.55 [0.76, 8.53]
2 Citalopram versus heterocyclics	2	432	Odds Ratio (M‐H, Random, 95% CI)	0.63 [0.24, 1.69]
2.1 versus Maprotiline	1	96	Odds Ratio (M‐H, Random, 95% CI)	0.64 [0.17, 2.42]
2.2 versus Mianserin	1	336	Odds Ratio (M‐H, Random, 95% CI)	0.63 [0.15, 2.68]
3 Citalopram versus other SSRIs	14		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
3.1 Versus Escitalopram	8	2206	Odds Ratio (M‐H, Random, 95% CI)	0.80 [0.38, 1.66]
3.2 Versus Fluoxetine	3	732	Odds Ratio (M‐H, Random, 95% CI)	1.15 [0.64, 2.08]
3.3 Versus Paroxetine	1	406	Odds Ratio (M‐H, Random, 95% CI)	0.57 [0.13, 2.42]
3.4 Versus Sertraline	3	760	Odds Ratio (M‐H, Random, 95% CI)	0.73 [0.34, 1.60]
4 Citalopram versus other conventional ADs	3		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
4.1 versus Mirtazapine	1	270	Odds Ratio (M‐H, Random, 95% CI)	0.25 [0.03, 2.28]
4.2 versus Reboxetine	2	458	Odds Ratio (M‐H, Random, 95% CI)	0.66 [0.17, 2.57]