Comparison 46. SE ‐ Headache.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Citalopram versus TCAs	6	606	Odds Ratio (M‐H, Random, 95% CI)	1.37 [0.78, 2.42]
1.1 versus Amitriptyline	4	528	Odds Ratio (M‐H, Random, 95% CI)	1.25 [0.65, 2.42]
1.2 versus Imipramine	1	43	Odds Ratio (M‐H, Random, 95% CI)	3.56 [0.63, 20.15]
1.3 versus Nortriptyline	1	35	Odds Ratio (M‐H, Random, 95% CI)	1.08 [0.25, 4.70]
2 Citalopram versus heterocyclics	2	432	Odds Ratio (M‐H, Random, 95% CI)	1.27 [0.62, 2.60]
2.1 versus Maprotiline	1	96	Odds Ratio (M‐H, Random, 95% CI)	2.14 [0.50, 9.12]
2.2 versus Mianserin	1	336	Odds Ratio (M‐H, Random, 95% CI)	1.07 [0.46, 2.45]
3 Citalopram versus other SSRIs	11		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
3.1 Versus Escitalopram	5	1261	Odds Ratio (M‐H, Random, 95% CI)	1.08 [0.64, 1.81]
3.2 Versus Fluoxetine	3	732	Odds Ratio (M‐H, Random, 95% CI)	0.90 [0.51, 1.60]
3.3 Versus Paroxetine	1	406	Odds Ratio (M‐H, Random, 95% CI)	1.24 [0.79, 1.96]
3.4 Versus Sertraline	3	587	Odds Ratio (M‐H, Random, 95% CI)	0.55 [0.33, 0.91]
4 Citalopram versus IMAOs or newer ADs	1		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
4.1 versus Moclobemide	1	42	Odds Ratio (M‐H, Random, 95% CI)	0.16 [0.01, 3.64]
5 Citalopram versusother conventional ADs	3		Odds Ratio (M‐H, Random, 95% CI)	Subtotals only
5.1 versus Mirtazapine	1	270	Odds Ratio (M‐H, Random, 95% CI)	1.59 [0.75, 3.37]
5.2 versus Reboxetine	2	458	Odds Ratio (M‐H, Random, 95% CI)	0.50 [0.25, 1.00]