Table 3.
Developmental Outcome
| Case | Age at Time 1 in months | Vineland Adaptive Behavior Composite | MDI | PDI | Stanford -Binet | Age at Time 2 in months | Vineland Adaptive Behavior Composite | MDI | PDI | Stanford -Binet | Developmental Outcome |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Newborn Screened | |||||||||||
| Case 1 | 6 | NA | 88 | 73 | - | 20 | 87 | 110 | 90 | - | Normal at 3 years |
| Case 2 | 6 | 112 | 100 | 88 | - | 20 | 95 | 102 | 113 | - | Normal at 4 years |
| Case 3 | 6 | 119 | 145 | 117 | - | NA | - | - | - | - | Normal at 1 year |
| Case 4 | 9 | 110 | 111 | 102 | - | 21 | 95 | 112 | 116 | - | Normal at 29 months |
| Case 5 | 15 | 114 | 113 | 113 | - | 29 | 106 | 96 | 87 | - | Normal at 29 months |
| Case 6 | 5 | 118 | 102 | 94 | - | 15 | 109 | 107 | 121 | - | Normal at 15 months |
| Case 7 | 16 | 85 | 98 | 59 | - | - | - | - | - | - | Language delay at 26 months |
| Case 8 | NA | - | - | - | - | NA | - | - | - | - | Normal at 20 months |
| Identified because of Clinical Symptoms | |||||||||||
| Case 9 | 26 | 91 | 103 | 104 | - | 41 | 105 | - | - | 124 | Normal at 4 years |
| Case 10 | 21 | 64 | 49 | 49 | - | 32 | 51 | - | - | - | Autism, mental retardation and delays in language and motor skills at 6 years |
| Case 11 | 48 | 108 | - | - | 95 | 64 | 94 | - | - | 116 | Normal at 5 years |
| Case 12 | 56 | 71 | - | - | 110 | 67 | 64 | - | - | 85 | Hypotonia, learning disabilities at 8 yrs |
| Case 13 | 70 | 37 | - | - | 36 | 90 | 38 | - | - | 51 | Mental retardation and delays in language and motor skills at 8 yrs |
| Case 14 | 35 | 45 | 49 | 49 | - | 49 | 42 | 49 | 49 | - | Mental retardation (non-verbal, non-ambulatory) at 4 years, Rett Syndrome |
Time 1 = age at time of first study assessment ; Time 2 = age at time of second study assessment
MDI = Mental Development Index from the Bayley Scales of Infant Development
PDI = Psychomotor Development Index from the Bayley Scales of Infant Development