Table 5.
Odds ratios for AD as a function of the -386G/A P3 promoter polymorphism stratified by the presence or absence of APOE ε4 alleles
-386G/A genotype | APOE 4/4 | APOE -/4 | APOE -/- |
AA | 1.0 | 1.0 | 1.0 |
AG | 0.2; 0.02–2.6 | 1.2; 0.6–1.9 | 1.2; 0.9–1.7 |
GG | 0.8; 0.04–16.9 | 2.3; 1.2–4.8* | 1.6; 1.0–2.4* |
* p = 0.02 The APOE ε2 and ε3 alleles are designated as (-)