Table 2. Characteristics of patients within included studies with established RA, stratified by data source.
Reference | Female (%) |
Caucasian (%) |
Age (years) |
Disease duration (years) |
RF+ (%) |
DAS score (mean (SD)) |
HAQ score (mean (SD)) |
Physician type |
DMARD use (%) |
Combination DMARDs |
Biologic DMARDs |
Most common DMARD |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Studies of Registries or Clinics | ||||||||||||
Yelin 2005 | 83 | 83 | 62 | 20 | - | - | 1.1 (-) | Rheum | 90 | - | 32 | MTX |
Goycochea-Robles 2007 | 85 | - | 48 | 10 | - | 3.9 (1.3) | 1.2 (0.8) | Rheum | 93 | 41 | 6 | MTX |
Kahn 2007 | 78 | 83 | 54 | 10 | - | - | - | Rheum | 85 | - | 28 | - |
Yamanaka 2007 | 84 | - | 59 | 12 | - | 3.6 (-) | 0.8 (-) | Rheum | 90 | - | 3 | MTX |
Gonzalez-Alvaro 2008 | 72 | - | 61 | 13 | 75 | 4.1 (1.4) | 1.2 (0.9) | Rheum | 84 | 24 | 16 | MTX |
Sokka 2008(a) | 71 | - | 54 | 6 | 70 | - | 0.6 (0.5, 0.7)*¥ | Rheum | 91 | 12 | 6 | MTX |
Teh 2008 | 84 | 0 | 53 | 5 | 66 | 4.3 (1.3) | - | Rheum | 100 | 36 | 0 | MTX |
DeWitt 2009 | 78 | 87 | 65 | 24 | - | - | 1.4 (-) | Rheum | 73 | - | 41 | - |
Soderlin 2010 | 74 | - | 63 | 14 | - | - | 0.75 (0.25–1.25)* | Rheum | 87 | - | 20 | MTX |
Ziegler 2010 | 76 | - | 62 | 11 | - | 3.4 (1.3) | - | Rheum | 85 | 23 | 16 | MTX |
Montag 2011 | 69 | - | 60 | - | - | - | Rheum | 92 | 26 | 15 | MTX | |
Sung 2012 | 85 | - | 54 | 8 | 87 | 3.8 (1.4) | 0.7 (0.7) | Rheum | 98 | 67 | 6 | MTX |
| ||||||||||||
Studies Using Administrative Data | ||||||||||||
| ||||||||||||
Edwards 2005 | 71 | - | 58 | 9 | - | - | - | Mixed | 50 | - | - | SSZ |
Khanna 2007 | 77 | 95 | 47 | - | - | - | - | Mixed | 40 | - | 12 | - |
Schmajuk 2007 | 88 | 94 | >65 | - | - | - | - | Mixed | 30 | - | 6 | MTX |
Grijalva 2008 | 78 | 74 | 57 | - | - | - | - | Mixed | 52 | - | 16 | MTX |
Schmajuk 2011 | 75 | 82 | 74 | - | - | - | - | Mixed | 63 | - | - | - |
| ||||||||||||
Studies Using Population-Based
Surveys |
||||||||||||
| ||||||||||||
Westhoff 2009 | - | - | - | 9 | 41 | 2.9 (1.0) | - | Mixed | 59 | - | - | - |
Della Rossa 2010 | 68 | - | 66 | 14 | - | 4.0 (-) | 1.2 (-) | Mixed | 73 § | 5 | - | MTX |
Solomon 2012 | 76 | 82 | >45 | - | - | - | Mixed | 47 | - | 15 | - |
- : not reported
DMARD: disease modifying drug
RF+: rheumatoid factor positive; DAS: disease activity score; HAQ: Health Activity Questionnaire;
Rheum: Rheumatologists; Mixed: Not restricted to rheumatologists; MTX: methotrexate; SSZ: sulfasalazine Numbers in italics are approximated from study data
mean(SD) not available; median (IQR) reported instead
MHAQ reported instead of HAQ
personal communication ADR