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. 2014 Oct 21;9(10):e109449. doi: 10.1371/journal.pone.0109449

Table 3. Multivariate Cox regression analysis on 3-year disease-free survival of 218 patients with breast cancer (including intensity and proportion of GILT expression).

Variable HR 95%CI ?2 P
Lower Upper
Intensity of GILT 3.372 1.212 9.384 5.421 0.020
Proportion of GILT 1.804 0.539 6.043 0.916 0.339
TIL score 2.474 0.938 6.524 3.353 0.067
Disease side 0.841 0.321 2.205 0.124 0.725
Age 1.089 0.423 2.803 0.032 0.859
BMI a 2.569 1.370 4.816 8.656 0.003
Menarche 3.389 0.660 17.400 2.139 0.144
Menopause 1.088 0.308 3.838 0.017 0.896
Hypertension 0.300 0.034 2.645 1.175 0.278
Diabetes mellitus 0.687 0.076 6.246 0.111 0.739
Peripheral blood neutrophils 2.187 0.571 8.383 1.303 0.254
Peripheral blood lymphocytes 1.356 0.451 4.079 0.294 0.588
Peripheral blood hemoglobin 1.423 0.454 4.467 0.366 0.545
Histological type 1.269 0.264 6.113 0.088 0.766
pTNM stage 4.343 1.913 9.860 12.319 <0.001
Molecular classification 1.372 0.971 1.939 3.208 0.073

Abbreviations: HR, hazard ratio; CI, confidence interval; TIL, tumor infiltrating lymphocyte; BMI, body mass index; pTNM stage, pathological TNM stage.

a

the international BMI classification.