Figure 5. T-cell trafficking following delayed immunologic challenge.

4T1 sensitized T cells expanded in IL-2 containing media, were injected in naive mice one week prior to 4T1 challenge. (A) The labeled 4T1 specific T cells were able to leave the lymphoid compartments and localize within 2 hours at the site of an immunologic challenge induced by 4T1 cell implantation in the flank. (B) Tumor/Background ratios obtained from mice injected with T cells and implanted with 4T1 cells a week later.