Table 5. The analysis of changes in cytokines concentration after and before surgery.
Changes in the cytokines concentration | PPS (n = 49) | No PPS (n = 26) | P value* | ||
Median (Q1–Q3) | P value | Median (Q1–Q3) | P value | ||
IL-8 | 33.3 (17.3–50.6) | <0.0001 | 13.5 (8.43–23.8) | 0.04 | 0.006 |
IL-1β | 1.82 (0–6.4) | 0.001 | 0 ([−3.3]–4.9) | 0.79 | 0.049 |
IL-6 | 27.56 (16.7–60.1) | <0.0001 | 21.93 (13.9–40.3) | 0.0005 | 0.22 |
IL-10 | 1.63 (0–9.9) | <0.0001 | 1.18 ([−0.7]−3) | 0.16 | 0.21 |
TNF | 0.3 (0–9.16) | <0.0001 | 0 (0–4.75) | 0.33 | 0.3 |
IL-12p70 | 0 (0–6.66) | <0.0001 | 0 (0–0.9) | 0.65 | 0.27 |
PPS-patients with the postpericardiotomy syndrome, No PPS- patients without the postpericardiotomy syndrome, P value-changes of cytokines after and before surgery tested by sign test, P value*- the differences of cytokine changes in patents with and without PPS tested by Wilcoxon test, n- numbers of patients.