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. 2014 Oct 21;9(10):e109693. doi: 10.1371/journal.pone.0109693

Table 3. Circadian parameters of Per2 promoter activities based on four days of data in Caki-2 cells.

period (h) amplitude acrophase (h) P value
control 24.3±0.04 1045.57±41.99 5.49±0.10 <0.000001
+chrysin100 µM 24.2±0.04 766.08±23.95* 5.74±0.11 <0.000001

Period, amplitude, and acrophase of the oscillations were measured on days 2 to 5 using the Cosinor software (Circadian Rhythm Laboratory). Amplitude significantly decreased (mean ± SEM, n = 4) compared to the control (* p<0.05).