Table 3. Circadian parameters of Per2 promoter activities based on four days of data in Caki-2 cells.
period (h) | amplitude | acrophase (h) | P value | |
control | 24.3±0.04 | 1045.57±41.99 | 5.49±0.10 | <0.000001 |
+chrysin100 µM | 24.2±0.04 | 766.08±23.95* | 5.74±0.11 | <0.000001 |
Period, amplitude, and acrophase of the oscillations were measured on days 2 to 5 using the Cosinor software (Circadian Rhythm Laboratory). Amplitude significantly decreased (mean ± SEM, n = 4) compared to the control (* p<0.05).