Table 1. Phenotypes that result from the 16 combinations of the four motility mechanisms (a)–(d) and the four conversion rules (i)–(iv).

Conversion Rule Used in Cortical Layer	Movement Rule in Cortical Layer
	(a) Unbiased random				(b) Bias due to				(c) Layer 1 attracting				(d) Layer 1 repelling
	movement				chemoattractant				sensing bias				sensing bias
	WT	R	D	DC	WT	R	D	DC	WT	R	D	DC	WT	R	D	DC
(i) Global at random	X	√	X	X	✓	√	√	X	✓	√	√	X	X	√	X
(ii) Local at random		√	X	√	✓	√	√	√	✓	√	√	√	X	√	X	√
(iii) Stop signal	√	X	X	X	✓	X	X	X	✓	X	X	X	√	X	X	X
(iv) Stop signal + local	√	√	X	X	✓	√	√	X	✓	√	√	X	√	√	X	√

Combinations that successfully reproduce a phenotype over a range parameter values are shown with tick marks (√). The two columns in which the tick marks are shown in an enlarged size correspond to especially informative predictions. Combinations that sometimes reproduce the experimental observations are shown with bullets (). Failure to reproduce the experimental observation is shown with a cross (X). The row in which the crosses are shown in an enlarged size corresponds to especially informative predictions. The phenotypes considered are: WT  =  Wild-type, R  =  reeler mutant, D  =  Dab1 mutant and D^C  =  Dab1 conditional mutant. Note, for the Reelin signalling mutants, mechanism (iv) converts to (ii).