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. 2014 Oct 21;9(10):e110483. doi: 10.1371/journal.pone.0110483

Figure 5. Attenuation of SLD5 expression induces marked DNA damage in cancer cells.

Figure 5

Western blot analysis of γ-H2AX expression in SCR or SLD5 siRNA-transfected B16 (A, B) or Colon26 (C, D) cells after treatment with etoposide (ETO) or control vehicle (DMSO). β-actin was the internal control. Data were quantitatively evaluated based on densitometric analysis (B, D). Results are fold-change compared with the level seen in SCR siRNA-treated B16 cells (B) or Colon26 cells (D), respectively. Data represent the mean ± SD. *, P<0.05 (n = 3).