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. 2014 Sep 23;53(41):6496–6510. doi: 10.1021/bi500739q

Table 3. Subunit Exchange Kinetic Analysis between WT and FT2·WT TTR and between V122I and FT2·V122I TTRa.

  FT2-homotetramer disappearanceb nontagged TTR disappearanceb 2 FT2/2 TTR (heterotetramer) formationb
WT/FT2·WT TTR 6.49 ± 0.42 10.21 ± 3.46 12.54 ± 4.71
V122I/FT2·V122I TTR 1.92 ± 0.14 2.28 ± 0.37 2.84 ± 0.62
b

Calculated half-time (t50, h) for the disappearance of the homotetramers FT2 and untagged homotetramers and the appearance of the heterotetramer composed of 2 FT2 subunits and 2 untagged subunits.