Electropherograms
and raw peak area data demonstrating sample clearing
and indexing for screening by MCE. (A) Electropherograms showing injection
and separation of rhodamine (R), substrate (S), and product (P) and
transition from a sample without rhodamine to a sample with rhodamine
demonstrating complete sample clearing by two droplets. (B) Extracted
peak areas for rhodamine (black trace), substrate (red trace), and
product (blue trace) for analysis of 12 samples, two controls and
ten test compounds. Changes in rhodamine peak height were used to
determine start and end points for each compound to calculate reaction
yield.