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. 2014 Aug 11;47(10):2941–2950. doi: 10.1021/ar5001617

Figure 2.

Figure 2

(a, b) Configuration of 1st-gen NanoVelcro CTC chip. The device is composed of a patterned NanoVelcro substrate and an overlaid PDMS chaotic mixer. (c) CTCs (DAPI+/CK+/CD45–, sizes >6 μm) can be clearly distinguished from nonspecifically captured WBCs (DAPI+/CK–/CD45+, sizes <12 μm) by a three-color ICC protocol. (d) Fluorescent images of two prostate cancer CTCs captured on the substrate along with nonspecifically captured WBCs.