Figure 4. Summary representations of patients' ability to engage in episodic future thinking (left: disturbed; right: spared) depicting (A) localization of preserved (+) or atrophied (−) brain regions and associated hypothesized function (superior medial prefrontal cortex (mPFC): coherent context processing; hippocampus: binding; amygdala: emotional processing; lateral temporal cortex: semantic processing) and (B) brain activations for each patient compared to healthy elders for the contrast Future>Past thinking (see results on Table 6).
