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. 2014 Oct 21;9(10):e110977. doi: 10.1371/journal.pone.0110977

Figure 1. Kinetic changes and accumulation of serum BPA concentrations in WHHL rabbits.

Figure 1

(A) WHHL rabbits were fed BPA (400 µg/kg) by gavage, and serum levels of BPA were measured over the next 24 hr as described in the Materials and Methods section. Serum levels of BPA are expressed as the means ± SE. For each group, n = 6. (B) Serum levels of BPA were measured biweekly over the course of 12 weeks as described in the Materials and Methods section. Serum levels of BPA are expressed as the means ± SD, n = 6 for each group. Total exposure volumes during experiments are calculated as the areas under the curves (AUC’s) (shown in the insert). *p<0.05 vs. vehicle.