Skip to main content

View full-text article in PMC

. 2014 Oct 21;9(10):e110977. doi: 10.1371/journal.pone.0110977

Table 1. Serum pharmacokinetic parameters for unconjugated BPA in WHHL rabbits compared with monkey and mice.

Species	Gender	Age	BPA (µg/kg)	C_max (ng/mL)^a	Terminalt½ (hr)^b	AverageAUC_0–24 (ng/mL)^c	References
WHHL rabbit	Male	Adult	400	3.41	18.44	1.22	This study
CD-1mice	Female	Adult	400	3.28	33.64	0.70	[27]
Rhesusmonkey	Female	Adult	400	3.95	8.88	0.52	[27]
CD-1mice	Female	Neonatal	395	14.82	9.35	2.78	[34]

^a

C_max: maximum attained value; ^bTerminal t½: the terminal phase half-life;

^c

AUC_0–24: the area under the curve at t = 24 hr after gavage.