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. Author manuscript; available in PMC: 2014 Oct 21.
Published in final edited form as: Ann N Y Acad Sci. 2013 Mar;1279:54–59. doi: 10.1111/nyas.12053

Figure 1.

Figure 1

Deletion of GluA1 from mice results in motor neurons with a smaller and simplified dendritic arbor (from Ref. 20). Spinal motor neurons of GluA1−/− mice compared to WT mice at P23. Mice at P23 have motor neurons with significantly fewer branches (the average WT dendritic tree has 25 ± 1.6 branches, compared to that of GluA1−/−, which has only 16 ± 1.8 branches (P < 0.0001)) and a smaller total tree size (the average dendritic tree of WT has a total length of 4013 ± 1280 μM, compared to 2750 ± 997 μM in the GluA1−/− mice (P < 0.05)). This effect is unique to the dendritic arbor, in that motor neuron soma size remains unchanged.