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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Glia. 2014 Jul 17;62(12):2034–2043. doi: 10.1002/glia.22724

Figure 4.

Figure 4

Dopaminergic neuroprotection by post-treatment with subpicomolar DPI 24 h after xenobiotic damage in primary neuron-glia cultures. (A) Experimental designs. Midbrain neuron-glia cultures were pre-treated with LPS (20 ng/ml), MPP+ (0.15 μM) or rotenone (10 nM) for 24 h, followed by DPI (10−14 or 10−13 M) treatment. (B–D) Seven days after DPI treatment, significant dopaminergic protection was observed using the [3H]-DA uptake assay. The results are expressed as a percentage of the controls and are the mean ± SEM from three to four experiments performed in duplicate. Data were analyzed using one-way ANOVA, followed by Bonferroni’s post hoc multiple comparison test. *p < 0.05, **p < 0.01.