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. Author manuscript; available in PMC: 2014 Nov 1.
Published in final edited form as: Mucosal Immunol. 2014 Apr 23;7(6):1386–1394. doi: 10.1038/mi.2014.28

Figure 4.

Figure 4

Aged dendritic cell (DC) supernatants express enhanced levels of pro-inflammatory mediators and metalloproteinases. Bar graphs depict the level of cytokines, chemokines, and metalloproteinases present in unstimulated aged (Ag) and young (Yg) DC supernatants (sup) as determined by ELISA. (a) Tumor necrosis factor (TNF)-α; (b) interleukin (IL)-6; (c) CXCL10; (d) CXCL8; (e) CCL2; (f) IL12p40; (h) A disintegrin family of metalloproteinase 10 (ADAM10). Data are mean±s.e. of 25 aged and 25 young subjects. Bar graphs depict the gene expression of metalloproteinases in aged and young DCs; (g) ADAMs. Data are mean±s.e. of 12 aged and 12 young subjects.