Table 2.
Comparison of 226 patients with bloodstream infections with 1325 patients without BSI
| BSI (N=226) | No BSI (N=1325) | p-value | |||
|---|---|---|---|---|---|
| Age | 40.5 (30.0–51.0) | 39.0 (29.0–50.0) | 0.49 | ||
| Female | 143 (63.3%) | 923 (69.7%) | 0.06 | ||
| Etiology | 0.30 | ||||
| APAP | 100 (44.3%) | 619 (46.7%) | |||
| Viral Hepatitis | 15 (6.6%) | 138 (10.4%) | |||
| DILI | 27 (12.0%) | 147 (11.1%) | |||
| Indeterminate | 34 (15.0%) | 172 (13.0%) | |||
| Other | 50 (22.1%) | 249 (18.8%) | |||
| Biochemistry* | |||||
| APACHE II | 17.0 (14.0–22.0) | 15.0 (10.0–21.0) | 0.02 | ||
| MELD | 31.7 (26.0–38.1) | 31.7 (24.5–38.8) | 0.96 | ||
| INR | 2.6 (1.9–4.1) | 2.7 (2.0–4.2) | 0.14 | ||
| Bilirubin (mg/dl) | 7.6 (4.1–20.2) | 7.3 (3.7–20.5) | 0.50 | ||
| Creatinine (mg/dl) | 1.8 (1.0–3.1) | 1.6 (0.9–3.1) | 0.14 | ||
| Lactate (mg/dl) | 4.9 (2.8–10.9) | 4.4 (2.5–9.5) | 0.10 | ||
| ALT (U/L) | 1461.0 (492.5–3794.5) | 2076.5 (674.0–4645.0) | 0.02 | ||
| WBC | 10.3 (6.8–16.3) | 10.5 (7.2–15.1) | 0.86 | ||
| Platelet Count | 120.0 (81.0–187.0) | 133.0 (87.0–197.0) | 0.07 | ||
| Organ Support | |||||
| Mechanical Ventilation | |||||
| Admission* | 128 (56.9%) | 579 (43.9%) | <0.001 | ||
| 7-days** | 164 (72.6%) | 780 (58.9%) | 0.0001 | ||
| Vasopressors | |||||
| Admission* | 51 (23.0%) | 242 (18.6%) | 0.13 | ||
| 7-days** | 95 (42.4%) | 418 (31.7%) | 0.002 | ||
| Renal Replacement Therapy | |||||
| Admission* | 50 (22.3%) | 271 (20.7%) | 0.57 | ||
| 7-days** | 79 (35.1%) | 443 (33.6%) | 0.65 | ||
| Antimicrobial Prophylaxis** | 77 (34.1%) | 523 (39.5%) | 0.12 | ||
| Coma Grade* | 0.002 | ||||
| 1 or 2 (Low) | 96 (42.5%) | 711 (53.8%) | |||
| 3 or 4 (High) | 130 (57.5%) | 610 (46.2%) | |||
- Normally distributed data presented as mean (Standard deviation)
- Non-normally distributed data presented as Median (IQR)
- Categorical data presented as percentage (chi-square test)
- *~On admission
- **~During 7-day inpatient phase
- ***~21-day post-enrollment