Table 4. Association of DRD3 Ser9Gly polymorphism with utilization.
| DRD3 Ser9Gly genotypes with utilization. | ||||
|---|---|---|---|---|
| Utilization | Genotype, n (%) | p-value | ||
| Gly/Gly | Gly/Ser | Ser/Ser | ||
| 0 | 3 (17.6) | 13 (76.5) | 1 (5.9) | 0.061a |
| ≥1 | 52 (46.0) | 52 (46.0) | 9 (8.0) | |
| DRD3 Ser9Gly alleles with utilization. | ||||
| Utilization | Allele, n (%) | OR(95% CI) | p-value | |
| Gly | Ser | |||
| 0 | 19 (55.9) | 15 (44.1) | 0.57 (0.27, 1.18) | 0.128b |
| ≥1 | 156 (69.0) | 70 (31.0) | ||
| DRD3 Ser9Gly heterozygotes & homozygotes with utilization. | ||||
| Utilization | Heterozygotes, n(%) | Homozygotes, n(%) | OR (95% CI) | p-value |
| 0 | 13 (76.5) | 4 (23.5) | 3.81 (1.17, 12.41) | 0.035a |
| ≥1 | 52 (46.0) | 61 (54.0) | ||
Dopamine D3 receptor (DRD3). Odds ratio (OR). Confidence interval (CI).
a
Fisher's exact test;
b
2-sided chi-square test.