Table 1.
Correlation of MUC4 expression with clinicopathological characteristics of patients
| Patient characteristics | MUC4 Negative (n=19) N (%) | MUC4 Positive (n=68) N (%) | p-value |
|---|---|---|---|
| Age (median 59.5, range 42-95) | |||
| <58 years | 8 (42%) | 31 (46%) | 0.75 |
| ≥58 years | 11 (58%) | 36 (54%) | |
| Race | |||
| African American | 7 (37%) | 20 (29%) | 0.83 |
| White | 11 (58%) | 44 (65%) | |
| Unknown | 1 (5%) | 4 (6%) | |
| Sex | |||
| Male | 12 (92%) | 49 (73%) | 0.40 |
| Female | 7 (8%) | 18 (27%) | |
| Tobacco | |||
| Never | 5 (28%) | 12 (18%) | |
| Current | 12 (67%) | 37 (56%) | 0.23 |
| Former | 1 (6%) | 17 (26%) | |
| Site Group 1 | |||
| Oral cavity | 6 (32%) | 13 (19%) | |
| Oropharyngeal | 13 (68%) | 55 (81%) | 0.25 |
| Site Group 2 | |||
| Oral cavity | 8 (42%) | 13 (19%) | |
| Base of tongue | 1 (5%) | 18 (26%) | |
| Tonsil | 5 (26%) | 28 (41%) | N/A |
| Pharynx | 5 (26%) | 9 (13%) | |
| Grade | |||
| Well differentiated | 1 (6%) | 6 (9%) | |
| Moderately differentiated | 9 (5O%) | 38 (59%) | 0.56 |
| Poorly differentiated | 8 (44%) | 20 (31%) | |
| T-stage | |||
| T1/T2 | 7 (41%) | 32 (51%) | |
| T3/T4 | 10 (59%) | 31 (49%) | 0.48 |
| N-stage | |||
| NO | 5 (29%) | 17 (27%) | |
| N1-N3 | 12 (71%) | 46 (73%) | 0.84 |
N/A - analysis not conducted because of unstable OR estimates due to small sample size.