Table 1.
Demographics and Clinical Characteristics of AD Subjects
| Subject # | Disease state | Age (y) | Gender | ApoE | PMI (h) | Braak Stage | MMSE | NFT | Diffuse plaques | Neuritic plaques |
|---|---|---|---|---|---|---|---|---|---|---|
| 1180 | AD | 91 | F | 3/3 | 3.00 | 6 | 1 | 15.6 | 50 | 16.4 |
| 1185 | AD | 79 | F | 4/4 | 3.00 | 6 | 10 | 26.2 | 49 | 13.2 |
| 1188 | AD | 75 | F | 3/4 | 2.50 | 6 | 1 | 36.5 | 50 | 15.4 |
| 1196 | AD | 83 | F | 3/4 | 2.25 | 6 | 0 | 3.4 | 50 | 7 |
| 1202 | AD | 80 | F | 3/4 | 3.33 | 6 | 22 | 22.2 | 49.2 | 24.8 |
| 1093 | AD | 82 | F | 3/4 | 2.50 | 6 | 1 | 25.8 | 42.6 | 17.2 |
| 1092 | Norm | 86 | F | 3/3 | 1.75 | 0 | 29 | 0 | 0 | 0 |
| 1131 | Norm | 80 | F | 3/3 | 2.25 | 0 | 28 | 0 | 0 | 0 |
| 1163 | Norm | 84 | F | 3/3 | 3.00 | 0 | 26 | 0 | 0 | 0 |
Pathology reported is for frontal cortex.
PMI = post mortem interval; MMSE = Mini-Mental Status Exam; NFT = neurofibrillary tangles; ApoE = apoE genotype
Plaques per 10X objective field (2.35 mm2); tangles per 20X objective field (0.586 mm2).