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. 2014 Sep 21;12:266. doi: 10.1186/s12967-014-0266-2

Figure 6.

Figure 6

Model for regulation of MMP-9, MMP-13 and EMMPRIN by curcumin. PMA induced EMMPRIN, MMP-9 and MMP13 expression by macrophages through AMPK and PKC pathway.Curcumin attenuates expression of MMP-9, MMP-13 and EMMPRIN by inhibiting the activation of AMPK and PKC pathway.