Table 2.
Variable | n |
Activity of antioxidative enzymes (U/g tissue) |
Level of non-enzymatic antioxidants (nmol/g tissue) |
||||||
Cu, Zn-SOD | CAT | GSH-Px | GSSG-R | GSH | Vit.C | Vit.E | |||
Histological | Adc.G2 | 60 | 304±38b | 73±15a | 1892±583a | 759±242a | 151±37 | 439±85a | 31.9±9.5a |
type/grade of | Adc.G3 | 6 | 318±48d | 62±18c | 2005±591c | 795±228c | 143±35 | 407±92d | 29.7±9.2c |
colorectal cancer | Adc. muc | 15 | 363±72f,i | 40±14f,i,k | 2143±623f | 880±194f | 144±43 | 398±104f | 33.5±8.5e |
Clinical stage of | II | 46 | 237±42b | 76±14a | 1854±552a | 737±228a | 174±36a | 458±88a | 33.1±9.1a |
colorectal cancer | III | 29 | 289±47d,g | 57±16c,g | 1987±699c | 824±236c | 156±39c | 399±90d,g | 29.1±9.4c |
IV | 6 | 421±58f,i,k | 33±18f,i,k | 2467±368f,i | 951±243f,i | 150±48e | 325±92f,i | 13.3±10.3f,i,k | |
Control (normal colon mucosa) | 117±25 | 84±17 | 1723±189 | 625±112 | 167±15 | 513±64 | 37.5±5.2 |
Statistical differences: see Table 1.