Expression of Bax and Bcl-xl after infection with Ad-TIP30 and mock as control in the three cell lines. Lysates were collected at 0, 6, 8, 12, 24, 36 h after infection. Ad-TIP30 infection resulted in increased Bax protein expression which was at its peak at 12-24 h after infection in HepG2 cells (Figure 6A), and decreased Bcl-xl protein levels in three cell lines (Figures 6A-C).