Table 3.

Significant prognostic factors contributing to disease-free survival by multivariate Cox’s proportion-hazard regression model.

Variable	Coefficient	SE	Hazard ratio	P
Age (55 vs >55 yr)	-0.013	0.011	0.987	0.257
Sex (male vs female)	0.294	0.25	1.342	0.239
CCA type (mass-forming vs periductal-infiltrating)	0.44	0.322	1.552	0.173
Histology
Papillary	-0.83	0.471	0.436	0.078
Well differentiated	-0.891	0.402	0.41	0.027
Moderately differentiated	-0.736	0.462	0.479	0.111
Poorly differentiated	-0.356	0.405	0.701	0.379
Squamous/adenosquamous	0.264	0.756	1.302	0.727
Vascular invasion (present vs absent)	-0.234	0.272	0.791	0.39
Neural invasion (present vs absent)	-0.362	0.247	0.696	0.143
Lymphatic invasion (present vs absent)	0.053	0.313	1.055	0.865
Tissue sLea (present vs absent)	0.834	0.26	2.302	0.001