Table 1.
Systemic hemodynamic parameters, KICG values and splanchnic circulatory parameters before LDLT
| Parameters | Healthy individuals n = 16 | Group I n = 25 | Group II n = 5 |
| Systemic hemodynamics | |||
| CO (L/min) | 5.83 ± 1.52 | 6.87 ± 0.97a | 7.36 ± 1.07e |
| CI (L/min per m2) | 3.22 ± 0.71 | 4.10 ± 0.71b | 4.56 ± 0.58e |
| BV (L) | 3.40 ± 0.96 | 4.09 ± 0.51a | 4.40 ± 0.45e |
| CO/BV (/min) | 1.74 ± 0.28 | 1.69 ± 0.21 | 1.69 ± 0.28 |
| MTT (s) | 16.1 ± 2.3 | 16.5 ± 1.5 | 16.5 ± 1.2 |
| HR (beat/min) | 64.3 ± 9.9 | 77.9 ± 12.6b | 77.6 ± 9.8e |
| MAP (mmHg) | 89.3 ± 11.8 | 68.9 ± 6.5d | 70.8 ± 11.2e |
| TPR (dyne/s5 per cm) | 1275.1 ± 228.3 | 818.9 ± 166.7d | 785.3 ± 187.4e |
| ICG clearance test | |||
| KICG | 0.227 ± 0.076 | 0.037 ± 0.017d | 0.056 ± 0.038e |
| Splanchnic circulation | |||
| Portal vein | |||
| PVFVo (mL/min) | 1482.1 ± 335.6 | 327.3 ± 416.9d | 435.6 ± 592.6e |
| PVFVe (cm/s) | 45.1 ± 8.1 | 7.9 ± 12.8d | 10.5 ± 13.8f |
| Hepatic artery | |||
| HAPI | 0.95 ± 0.11 | 1.06 ± 0.28a | 1.16 ± 0.21e |
| HARI | 0.93 ± 0.26 | 1.04 ± 0.23a | 1.10 ± 0.10e |
There were no significant differences between Groups I and II in each parameter, respectively (P > 0.05, analyzed by Mann-Whitney’s U test ). Statistical differences between healthy individuals and Group I analyzed by Mann-Whitney’s U test (aP < 0.05,
P < 0.005,
P < 0.0005). Statistical differences between healthy individuals and Group II analyzed by Mann-Whitney’s U test (eP < 0.05,
P < 0.005). ICG: Indocyanine green; LDLT: Living-donor liver transplantation; CO: Cardiac output; CI: Cardiac index; BV: Blood volume; MTT: Mean transit time; HR: Heart rate; MAP: Mean arterial pressure; TPR: Total peripheral resistance; PVFVo: Portal veinous flow volume; PVFVe: Portal venous flow velocity; HAPI: Hepatic arterial pulsatility index; HARI: Hepatic arterial resistant index.