Table 2.
Clinical profile | Group I(n = 25) | Group II(n = 5) | P valuea |
Before LDLT | |||
Age | 51.8 ± 9.8 | 58.6 ± 3.5 | NS |
Body surface area (m2) | 1.69 ± 0.18 | 1.61 ± 0.12 | NS |
Child-Pugh score (points) | 9.2 ± 2.3 | 10.8 ± 2.2 | NS |
Model for end-stage liver disease score (points) | 17.6 ± 6.7 | 17.4 ± 7.1 | NS |
During LDLT | |||
Native liver weight (g) | 857.0 ± 227.5 | 946.0 ± 376.2 | NS |
Portal venous pressure before removal of native liver (mmHg) | 21.5 ± 4.7 | 24.6 ± 7.1 | NS |
Cold ischemic time (min) | 163.7 ± 79.0 | 139.6 ± 52.6 | NS |
Warm ischemic time (min) | 55.1 ± 16.7 | 45.8 ± 12.7 | NS |
Anhepatic phase (min) | 209.2 ± 104.9 | 184.4 ± 177.6 | NS |
Operative time (min) | 899.4 ± 126.7 | 933.4 ± 131.0 | NS |
Blood loss (mL) | 22515.7 ± 14200.5 | 22788.6 ± 19247.8 | NS |
Graft weight (g) | 687.8 ± 124.6 | 632.0 ± 72.9 | NS |
Graft-recipient weight ratio | 1.09 ± 0.21 | 1.23 ± 0.37 | NS |
After LDLT | |||
Intensive care unit stay (d) | 5.1 ± 1.9 | 35.6 ± 15.7 | < 0.005 |
%SLV based on CT volumetry | |||
2 wk after LDLT | 1.14 ± 0.22 | 1.07 ± 0.09 | NS |
4 wk after LDLT | 1.05 ± 0.15 | 1.17 ± 0.16 | NS |
LHL15 based on 99mTc-GSA liver scintigraphy | |||
2 wk after LDLT | 0.935 ± 0.026 | 0.846 ± 0.061 | < 0.005 |
4 wk after LDLT | 0.941 ± 0.017 | 0.751 ± 0.034 | < 0.005 |
Histopathological fraft parenchymal damage score (points) | |||
Within 4 wk after LDLT | 3.9 ± 1.4 | 10.6 ± 1.3 | < 0.005 |
Statistical differences between Groups I and II analyzed by Mann-Whitney’s U test (NS: P > 0.05). LDLT: Living-donor liver transplantation; SLV: Standard liver volume; CT: Computed tomographic; LHL15: The ratio of liver to heart-plus-liver radioactivity at 15 min; 99mTc-GSA: Technetium-99m-diethylenetriaminepenta-acetic acid-galactosyl-human serum albumin.