Table 1.
Outcomes and Demographics by the Five Magnetic Resonance Imaging-defined Clusters.1
| Clusters defined by cluster analysis of MRI findings |
||||||||
|---|---|---|---|---|---|---|---|---|
| In 16 years after MRI scan | Normal | Atrophy | Simple Infarct |
Leuko- araiosis |
Complex Infarct |
Total | Analysis of Variance |
|
| N=981 | N=891 | N=530 | N=460 | N=368 | N=3230 | F | p-value | |
| Years of Life | 12.8 | 11.4 | 11.2 | 10.4 | 8.4 | 11.3 | 71.5 | <0.0005 |
| Years Dead | 3.2 | 4.6 | 4.8 | 5.6 | 7.6 | 4.7 | 68.1 | <0.0005 |
| Years of Healthy Life | 9.0 | 7.8 | 7.2 | 7.0 | 5.2 | 8.0 | 47.5 | <0.0005 |
| Years of Sick Life | 3.8 | 3.6 | 4.0 | 3.4 | 3.2 | 3.7 | 4.2 | 0.002 |
| Years of Able Life | 9.9 | 8.8 | 8.2 | 7.1 | 5.2 | 8.4 | 68.0 | <0.0005 |
| Years of Not-able Life | 2.9 | 2.7 | 3.0 | 3.3 | 3.2 | 2.9 | 4.5 | 0.001 |
| Around time of MRI scan | ||||||||
| Age (y) | 73.0 | 75.3 | 74.6 | 76.4 | 78.1 | 75.0 | 94.9 | <0.0005 |
| Men (%) | 31 | 52 | 36 | 37 | 47 | 40 | 26.0 | <0.0005 |
| White (%) | 81 | 88 | 83 | 85 | 85 | 84 | 4.4 | 0.002 |
| Healthy (%) | 83 | 84 | 84 | 80 | 76 | 82 | 4.5 | 0.001 |
| Able (%) | 90 | 91 | 89 | 87 | 86 | 89 | 3.2 | 0.012 |
| Hypertension history (%) | 51 | 53 | 61 | 61 | 66 | 56 | 9.4 | <0.0005 |
MRI means magnetic resonance imaging; Healthy, self-reported health as excellent, very good or good; and Able, without any limitations with activities of daily living.