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. Author manuscript; available in PMC: 2014 Oct 22.
Published in final edited form as: Neurotoxicology. 2008 Jun 19;29(6):971–977. doi: 10.1016/j.neuro.2008.06.003

Figure 5.

Figure 5

The effect of the selective DAT inhibitor, WIN 35428, on the toxicity of Tat 1-86 in primary rat fetal midbrain cell cultures. Results presented as mean % of Calcein/Ethidium bromide fluorescence (Live/Dead ratio)vs non-treated control ± SEM, n of sister cultures analyzed = 7-17 per each variant of treatment. Two different doses of WIN 35428 (1 and 5 μM) used in these experiments were not toxic to cultured rat fetal midbrain neurons and did not enhance the toxicity of Tat 1-86 determined after 48 hour-exposure. *- marks the significant (P<0.05) difference between Tat-treated group or Tat+WIN 35428 –treated group and non-treated control group;