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. Author manuscript; available in PMC: 2014 Oct 22.
Published in final edited form as: Aldrichimica Acta. 2011;44(1):3–11.

Table 11.

Synthesis of Enatioenriched α-Chloro Acids

graphic file with name nihms522308t26.jpg
R X yield (%) ee (%)
Ph H/D 89/ 95 88/ 88
2-OMeC6H4 H/D 80/ 83 94/ 95
4-BocNHC6H4 H/D 78/ 75 78/ 79
Cyclopentyl H/D 89/ 90 94/ 95
Cyclohexyl H/D 85/ 88 94/ 95
CH2OBn H/D 78/ 75 88/ 89
CH2CH2Ph H/D 86/ 78 88/ 89
CH2CH2CH2CO2Et H/D 75/ 77 90/ 91