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Establishing the TCR affinity hierarchy. (A and B) Ten thousand naïve B3K508 T cells were transferred into CD45.1 congenic mice followed by infection with Lm.3K or Lm.variant strains. Low dose Lm.3K infection in B corresponds to 105 cfu. Mean number of B3K508 T cells recovered from spleen and lymph nodes over the first 8 d of infection. Data represent n ≥ 3 for each data point and are representative of two independent experiments.
