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Antigen affinity and effector T-cell differentiation. Ten thousand B3K508 T cells were transferred into congenic mice followed by infection with Lm.3K or Lm.P2A. (A–D) Representative flow cytometry plots of B3K508 T cells at day 6. (E) Absolute number of Th1 (T-bethighCXCR5−) and TFH (T-betlowCXCR5+) effectors recovered from spleen and lymph nodes at day 6. Data represent n ≥ 3 and are representative of three independent experiments. (*P < 0.05, ***P < 0.0001).
