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. 2014 Sep 29;111(41):14852–14857. doi: 10.1073/pnas.1403271111

Fig. 3.

Fig. 3.

Antigen affinity and early IL-2 induction. Two hundred thousand carboxyfluorescein succinimidyl ester (CFSE)-labeled B3K508 T cells were transferred into congenic mice followed by infection with Lm.3K or Lm.P2A. CD25 proliferation (A) and T-bet expression (B) were assessed by flow cytometry after 2 (A) and 3 (B) d. T-bet MFI is shown for T cells that have undergone at least one division. Data represent n = 3 for each data point and are representative of two independent experiments. (**P < 0.001, ***P < 0.0001).