Table 1.
Stimulation index of insulin specific T-cell clones in response to peptides and denatured protein
Clone no. | B:11-23R22E | B:11-23 | deINS |
T1D#3 C5 | 485 | 122 | 190 |
T1D#3 C8 | 327 | 5.3 | 110 |
T1D#4 C5 | 189.6 | 77.7 | 54.2 |
T1D#4 C6 | 212.0 | 37.1 | NT |
T1D#10 C1 | 278.2 | 9.6 | 48 |
T1D#10 C3 | 302.2 | 10.2 | 46.5 |
T1D#10 C8 | 634.5 | 83 | 149 |
T1D#15 C2 | 346.9 | 31.4 | NT |
Average ± SD | 347 ± 147 | 47 ± 43 | 100 ± 60 |
Reported values are stimulation index in response to stimulation with B:11-23R22E peptide (6 μM), B:11-23 peptide (6 μM), or deINS protein (1.7 μM) versus an unstimulated control.