Box-and-whisker plots (over all studies) depicting range of (a)
δ1,t2w (T2w signal intensity),
(b), δ1,adc (ADC value), and (c)
δ18,t2w (T2w Haralick energy);
within the AZ and within a bounding box local to the AZ. Note that the red line in the
middle of each box reflects the median difference value while the box is bounded by
25th and 75th percentile of difference values. The whisker plot
extends to the minimum and maximum difference values outside the box. The derived T2w
texture feature ((c)) expresses a markedly distinct difference signature within the AZ
compared to the region adjacent to the AZ (with minimal overlap), as opposed to the
original T2w and ADC parameters which do not.