Table 2. Hemodynamic Changes During Surgery.
Propofol (n = 30) | Midazolam (n = 30) | Control (n = 30) | P Value (between groups) a | |
---|---|---|---|---|
Systolic, mmHg | 0.67 | |||
Before anesthesia (basic) | 123.1 ± 10.3b | 124.7 ± 10.2 | 125.1 ± 10.9 | |
After induction of anesthesia | 108.2 ± 14.1 | 109.8 ± 11.6 | 110.6± 11.1 | |
Before drug administration | 107.7 ± 11.1 | 111.8 ± 9.7 | 109.3 ± 10.6 | |
After drug administration | 102.4 ± 19.3 | 101.4 ± 19.1 | 107.5 ± 8.8 | |
Diastolic, mmHg | 0.81 | |||
Before anesthesia (basic) | 79.2 ± 10.8 | 78.0 ± 9.7 | 80.6 ± 9.07 | |
After induction of anaesthesia | 63.7 ± 12.0 | 63.4 ± 12.7 | 64.4 ± 12.4 | |
Before drug administration | 63.5 ± 12.9 | 63.0 ± 10.6 | 61.2 ± 10.6 | |
After drug administration | 55.0 ± 9.4 | 53.5 ± 11.8 | 59.4 ± 10.9 | |
Mean, mmHg | 0.21 | |||
Before anesthesia (basic) | 90.8 ±12.8 | 91.8 ± 11.4 | 97.0 ± 8.8 | |
After induction of anesthesia | 76.4 ± 14.4 | 79.4 ± 11.2 | 79.7 ± 11.4 | |
Before drug administration | 75.2 ± 11.0 | 77.8 ± 9.4 | 74.7 ± 10.7 | |
After drug administration | 70.1 ± 9.0 | 69.1 ± 10.5 | 73.4 ± 9.6 | |
HR, beat/min | 0.29 | |||
Before anesthesia (basic) | 99.6 ±17.1 | 97.2 ± 15.3 | 95.0 ± 14.6 | |
After induction of anesthesia | 101.9 ± 17.7 | 97.8 ± 18.0 | 95.6 ± 16.7 | |
Before drug administration | 99.0 ± 16.9 | 95.8 ± 16.7 | 95.7 ± 18.3 | |
After drug administration | 99.2 ± 16.8 | 99.1 ± 11.0 | 93.6 ± 13.3 | |
P value within groups a | ||||
BP | < 0.001 | < 0.001 | < 0.001 | |
HR | 0.79 | 0.83 | 0.41 |
aP < 0.05 is considered significant, between groups.
bData are presented as Mean ±SD.