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. 2014 Sep 16;4(4):e19384. doi: 10.5812/aapm.19384

Table 2. Hemodynamic Changes During Surgery.

Propofol (n = 30) Midazolam (n = 30) Control (n = 30) P Value (between groups) a
Systolic, mmHg 0.67
Before anesthesia (basic) 123.1 ± 10.3b 124.7 ± 10.2 125.1 ± 10.9
After induction of anesthesia 108.2 ± 14.1 109.8 ± 11.6 110.6± 11.1
Before drug administration 107.7 ± 11.1 111.8 ± 9.7 109.3 ± 10.6
After drug administration 102.4 ± 19.3 101.4 ± 19.1 107.5 ± 8.8
Diastolic, mmHg 0.81
Before anesthesia (basic) 79.2 ± 10.8 78.0 ± 9.7 80.6 ± 9.07
After induction of anaesthesia 63.7 ± 12.0 63.4 ± 12.7 64.4 ± 12.4
Before drug administration 63.5 ± 12.9 63.0 ± 10.6 61.2 ± 10.6
After drug administration 55.0 ± 9.4 53.5 ± 11.8 59.4 ± 10.9
Mean, mmHg 0.21
Before anesthesia (basic) 90.8 ±12.8 91.8 ± 11.4 97.0 ± 8.8
After induction of anesthesia 76.4 ± 14.4 79.4 ± 11.2 79.7 ± 11.4
Before drug administration 75.2 ± 11.0 77.8 ± 9.4 74.7 ± 10.7
After drug administration 70.1 ± 9.0 69.1 ± 10.5 73.4 ± 9.6
HR, beat/min 0.29
Before anesthesia (basic) 99.6 ±17.1 97.2 ± 15.3 95.0 ± 14.6
After induction of anesthesia 101.9 ± 17.7 97.8 ± 18.0 95.6 ± 16.7
Before drug administration 99.0 ± 16.9 95.8 ± 16.7 95.7 ± 18.3
After drug administration 99.2 ± 16.8 99.1 ± 11.0 93.6 ± 13.3
P value within groups a
BP < 0.001 < 0.001 < 0.001
HR 0.79 0.83 0.41

aP < 0.05 is considered significant, between groups.

bData are presented as Mean ±SD.