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. 2014 Oct 22;8:117. doi: 10.3389/fnana.2014.00117

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Copyright © 2014 Kelly, Opanashuk and Majewska.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Bisphenol-A exposure does not result in long lasting microglial activation. Immunofluorescent reactivity of microglial activation state markers following intracranial LPS injections (A–D), Oil (E–H), and BPA treatment (I–L). Notice that MHC II (A,B) and CD68 (I–L) are robustly expressed around the injection site in LPS treated tissue and show some co-localization with Iba-1. These markers are absent in oil and BPA-treated tissue. Arrows denote ramified microglia; arrowheads denote co-labeled (activated) microglia. Scale bar = 100 μm.