Figure 5. AAVpo6-LacZ transduce cells in the mouse lung parenchyma and airway epithelia.

AAVpo6-LacZ was instilled intranasally into mice at 1 × 10¹¹ gc/mouse. Lungs were harvested 28 d.p.i., frozen with O.C.T., and cryosectioned at 10 μm. Each section was stained with X-gal and eosin. Blue colored cells are indicative of transduced cells. (a) Airway epithelia, and (b, c) lung parenchyma.