Table 2. Neutralization antibody assay of porcine-derived AAVs and published AAVs against homologous or heterologous antisera and pooled human IgG.

	Vector
*Anti-sera	AAVpo2.1	AAVpo4	AAVpo5	AAVpo6	AAV5	AAV1	AAV6	AAV8
AAVpo1	<1:20	<1:20	<1:20	<1:20	<1:20	<1:20	<1:20	<1:20
AAVpo2.1	1:320	<1:20	<1:20	1:40	<1:20	<1:20	<1:20	<1:20
AAVpo4	<1:20	1:640	<1:20	<1:20	<1:20	<1:20	<1:20	<1:20
AAVpo5	<1:20	<1:20	1:40	<1:20	<1:20	<1:20	<1:20	<1:20
AAVpo6	<1:20	<1:20	<1:20	1:640	<1:20	<1:20	<1:20	<1:20
AAV5	<1:20	<1:20	<1:20	<1:20	1:5120	n/a	n/a	n/a
**Pooled Human IgG (mg/mL)	>12	>12	>12	1.5	0.1875	n/a	n/a	n/a

*Values represent dilution of anti-sera required to neutralize >50% of AAV-LacZ transducing particles.

**Values represent concentration of antibody in mg/mL, required to neutralize >50% of AAV-LacZ transducing particles.