Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Pain
Systematic review	34 women randomised, 32 women in analysis Data from 1 RCT	Pain relief with aspirin with naproxen Absolute results not reported	RR 2.29 95% CI 1.09 to 4.79	Moderate effect size	naproxen
Systematic review	96 women	Pain intensity continuous data (not further defined) with aspirin with fenoprofen Absolute results not reported	Mean difference 0.65 95% CI 0.10 to 1.20 P = 0.021	Effect size not calculated	fenoprofen
Systematic review	47 women Data from 1 RCT	Number of cycles where treatment gave moderate/good pain relief 13/89 (15%) with aspirin 42/90 (47%) with indomethacin	P <0.001 These data are per cycle rather than by participant	Effect size not calculated	indomethacin
Need for additional medication
Systematic review	96 women Data from 1 RCT	Additional analgesics required with aspirin with fenoprofen Absolute results not reported	OR 2.06 95% CI 0.73 to 5.83 P = 0.17		Not significant