Table 4.
Diagnostic accuracy
Correct diagnoses |
Diagnoses with high-probability (at least 2 of 3 observers)a) | |||
---|---|---|---|---|
Observer 1 | Observer 2 | Observer 3 | ||
Presence of abnormality on CT (n=207) | ||||
Sensitivity (%) | 88.4 | 81.6 | 91.3 | 86.8 |
Agreement (95% CI)b) | 0.85 (0.81-0.89) | |||
Diagnosis of infectious and noninfectious causes for lung abnormalities (n=151) | ||||
Sensitivity (%) | 69.5 | 68.9 | 71.5 | 70.2 |
Diagnosis of infectious pneumonia (n=150)c) | ||||
Sensitivity (%) | 63.0 | 63.0 | 65.0 | - |
Area under the ROC curve | 0.65 | 0.61 | 0.62 | - |
Sensitivity for each disease (%) | ||||
Fungal pneumonia | 66.0 | 52.8 | 60.4 | 66.0 |
Bacterial pneumonia | 68.4 | 60.5 | 73.7 | 62.5 |
Viral pneumonia | 57.1 | 78.6 | 64.3 | 73.8 |
Pneumocystis pneumonia | 60.0 | 60.0 | 60.0 | 60.0 |
CT, computed tomography; CI, confidence interval; ROC,receiver operating characteristic.
Cases of correct diagnoses reached by two or more observers,regardless of the degree of confidence,
Intraclass correlation coefficient,
139 patients had infectious cause, and more than two pathogens were identified in 11 patients.