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. 2014 Oct 22;9(10):e110509. doi: 10.1371/journal.pone.0110509

Table 2. Unconjugated BPA (uBPA) and glucuronidated BPA (BPA-G) pharmacokinetic parameters for 4 male and 2 female subjects who held thermal receipt paper and ate French fries after using hand sanitizer (shown in Figure 5-A).

Analyte Parameter Male Female All
Serum uBPA Baseline (ng/ml) 0.06±0.04 0.57±0.28 0.23±0.15
Cmax (ng/ml) 5.66±1.25 10.24±0.77 7.19±1.26
Maximum increase (ng/ml) 5.60±1.24 9.66±0.37 6.95±1.17
Range of increase (ng/ml) 3.96–9.28 9.29–10.03 3.96–10.03
Tmax (min) 60.00±12.25 15.00±0.00 45.00±12.25
Range of Tmax 30.00–90.00 15.00 15.00–90.00
Average AUC (0–90 min) (ng/ml) 3.92±1.08 3.85±0.04 3.90±0.75
Serum BPA-G Baseline (ng/ml) 0.60±0.10 2.95±0.91 1.38±0.55
Cmax (ng/ml) 1.49±0.39 7.74±1.75 3.57±1.42
Maximum increase (ng/ml) 0.89±0.36 4.79±0.85 2.19±0.88
Range of increase (ng/ml) 0.09–1.58 3.94–5.63 0.09–5.63
Tmax (min) 75.00±8.66 75.00±15.00 75.00±6.71
Range of Tmax 60.00–90.00 60.00–90.00 60.00–90.00
Average AUC (0–90 min) (ng/ml) 1.05±0.21 6.48±1.93 2.86±1.25
BPA-G/uBPA AUC (0–90 min) (ng/mL) 0.35±0.12 1.82±0.30 0.84±0.33
Urine Total BPA Baseline (ng/ml) 0.15±0.04 1.10±0.58 0.46±0.24
Baseline (µg/g creatinine) 0.20±0.09 1.22±0.24 0.54±0.19
90 min (ng/ml) 23.36±6.66 10.62±3.16 19.11±4.32
90 min (µg/g creatinine) 18.20±5.33 40.93±22.56 25.77±8.56

For these subjects blood was collected from the arm draining the hand that remained contaminated with BPA throughout the 90-min period of blood collection. Urine total BPA at baseline and at 90 min are presented as both actual concentration (ng/ml) and creatinine adjusted (µg BPA/g creatinine) values.

For the one female (Female #3; Figure 5-B) who had very high baseline serum uBPA (data not included in this table), the average serum AUC (0–90) values for uBPA and BPA-G were 6.05 and 4.49 ng/ml, respectively, and urine total BPA levels at baseline and at 90 min were 0.41 and 41.41-µg/g creatinine, respectively.